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But killing the bad guys responsible for your infection means you’re also killing the beneficial flora vital to your health. If you’ve recently taken a course of antibiotics and are wondering how long it will take to get your microbiome back to normal, or even if it’s possible, read on.
There are about 100 trillion bacteria in our gut, so it’s impossible to know the exact makeup of someone’s microbiome before or after starting a course of antibiotics. But modern gut tests can give us a good idea.
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Research has shown that antibiotics can kill the bacteria in our gut. This means that with a sinus infection, your period can reduce your gut flora to one-tenth of its previous level. Not a tenth, but a tenth, a 90% reduction (source: NCBI).
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Multiple courses of antibiotics appear to be the most harmful (source: NCBI), with higher doses of antibiotics taken over longer periods of time. This may come as shocking news to many people, usually teenagers, who have been taking antibiotics for months to treat acne.
Oluf Pedersen, lead scientist on a 2018 project that examined the effects of a course of antibiotics on the microbiome, noted that most people are exposed to multiple rounds of antibiotics. “This concern is related to the potential permanent loss of beneficial bacteria after multiple exposures to antibiotics throughout our lives,” he told reporters at the scientific news website ars TECHNICA (source: DX DOI).
If you see your doctor for an infection, you will likely be prescribed broad-spectrum antibiotics. This is because unless your doctor takes a sample and sends it to a lab for culture, they don’t know the type of bacteria that caused your infection. Prescribing a broad-spectrum antibiotic makes it more effective against your infection, but your gut bacteria will take a harder hit.
When researchers gave mice a broad-spectrum cephalosporin antibiotic or a combination of three antibiotics (amoxicillin, bismuth, and metronidazole), both antibiotic treatments led to significant changes in the gut microbiome.
How To Restore Gut Flora And Reset Your Gut After Antibiotics
Mice given broad-spectrum antibiotics did not regain their normal diversity, but other mice given the amoxicillin-containing combination mostly, but not completely, returned to pre-treatment levels (source: IAI.ASM).
Our first year appears to be critical to building a healthy microbiome for life. One study found a link between antibiotics given in the first year of life and later neurocognitive difficulties such as ADHD, depression and anxiety (source: Wiley). The more courses taken, the higher the risk of juvenile rheumatoid arthritis and inflammatory bowel disease (source: NCBI).
Others have linked antibiotic exposure in utero and early childhood (and subsequently altered gut microbiota) to the development of asthma later in life (source: BMJ) and obesity in children and adults (source: Science Direct).
In a healthy, diverse gut microbiome, the resident microbes help prevent the invasion of pathogens that can lead to infection or disease. Working together, they use different approaches to suppress pathogens, such as:
How To Restore Healthy Gut Flora With Probiotics!
These protective functions can be stopped when the gut microbes are depleted during antibiotic use. That’s when pathogenic bacteria can enter and upset the balance.
Research has revealed an interesting strategy that some bacteria use to re-establish themselves after antibiotics. They use resistance genes that scientists call “resistance genes” so that they never go away.
After trying to eliminate certain types of bacteria with antibiotics, scientists looked at the microbiome of 12 healthy men over a six-month period and noted collateral damage.
Initial changes included the “blooming” of some potentially harmful bacterial species, as well as the depletion of friendly bifidobacteria and butyrate-producing species. However, the subjects’ gut microbiota recovered within 1.5 months, returning to “almost” pristine levels, the researchers said.
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It is important to note, however, that nine common species present in all subjects before treatment remained undetectable in most subjects after 180 days (source: DX DOI).
There is no definitive way to restore gut bacteria after antibiotics. The reality is that despite rapid advances in microbiome science, there is still much we don’t know.
We know for sure, a healthy microbiome is diversity, and antibiotics definitely don’t encourage that. You can take care of your gut health in our gut health program and learn ways to improve the diversity of your microbiome.
Now let’s see what research can tell us about how to increase this diversity, with and without antibiotics.
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Some studies have shown that taking probiotics can reduce the risk of opportunistic pathogen invasion (source: NCBI) and antibiotic-associated diarrhea (source: JAMA). But it’s likely that different probiotic strains have different effects on different people.
Some probiotics have been shown to survive stomach acidity and reach the intestines, creating a protective barrier against potentially harmful bacteria. Culturelle is an example.
If you are taking antibiotics, the best time to take your probiotics is at least three hours apart. This gives probiotics the best chance of survival (source: NCBI).
Saccharomyces Boulardii is a beneficial yeast that can help suppress the proliferation of Candida, an opportunistic yeast, after a round of antibiotic treatment. A small amount of Candida is normally present in most people, but when given the chance, it can take over and cause problems. Saccharomyces boulardii has also been found to protect and repair the intestinal barrier (source: NCBI). Best of all, because it’s yeast, not bacteria, antibiotics won’t affect it at all.
Tips To Restore Gut Flora In 7 Days (natural And Science Backed)
Interestingly, a small recent study found that probiotics can actually inhibit the return of natural gut microbiota. The initial gut microbiome that was restored after 28 days in the probiotic group took longer to recover than the group that did not receive probiotics (source: Cell).
This particular study also looked at the benefits of a procedure called “faecal microbiota garage infusion” (aFMT), in which scientists regenerated participants by freezing their old poop (yes, poo) and returning it to the colon. Bacteria before antibiotics. The course is over.
Sounds crazy. According to the lead investigator, it “produced rapid and almost complete recovery within days of administration.” This evidence of the benefits of aFMT after antibiotics has prompted one UK clinic to offer stool freezing for people about to receive heavy antibiotic treatment.
Another strategy for restoring your gut microbiome after antibiotics is to make sure you eat well; with the foods your gut bugs love. This means eating foods that are high in prebiotics.
How To Reset Your Gut In 3 Days
Probiotics are food for the bacteria in our colon because they are not “further” digested in our small intestine. Probiotic foods are often rich in fiber and plant polyphenols. So eat lots of fruits, vegetables, legumes, nuts and whole grains.
You can also try prebiotic supplements such as inulin. a plant sugar that has been shown to reduce the diversity-killing effects of the antibiotic ampicillin in bacterial cultures (source: NCBI).
In a recent study, a team of Italian researchers compared the gut microbes of young villagers in Burkina Faso, Africa, with those of children in Florence, Italy. Peasants who ate mostly millet and sorghum (a whole grain) had more microbial diversity than Italians who ate a typical Western diet. They found that the bugs in the guts of Italian children adapted to protein, fat and simple sugars, while the microbiome in Burkina Faso favored fiber (source: NCBI).
One of the researchers in Burkina Faso wanted to learn more about the role of fiber in our microbiome, so they switched to another study where one group of mice was fed high fiber and the other sugar. Western diet. While the fiber-fed mice developed a more diverse microbiome, diversity dropped dramatically in mice fed a Western diet. Interestingly, they also reported that the fiber-deficient mice were also meaner and more difficult to handle. (Source: NCBI).
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The study found that stress triggers a fight-or-flight response that releases hormones in various parts of the body, which in turn affect the microbiome and reduce diversity (source: NCBI). To make matters worse, changes in gut microbial populations can affect neurotransmitter regulation, further exacerbating stress (source: NCBI).
Exercise changes the makeup of your microbiome. One study found that exercise can enrich the diversity of the microbiome and improve the balance of specific families of bacteria, which can aid in weight loss (Credit: Hindawi).
Furthermore, the researchers concluded that exercise promotes the growth of bacteria, which improves the integrity of the intestinal barrier and protects against gastrointestinal disease and colon cancer.
Most bacterial families seem to return to normal levels after about two months of treatment (source: NCBI). However, this answer is based on a study of the effects of a short course of antibiotics. We must remember that “many” bacterial families do not mean all, and missing families may play a key role in the delicate ecosystem of our gut (source: OUP), (source: ASM).
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